We litter-box train our puppies much like cats, with pine pellet litter. We begin litter box training between 3-4 weeks of age. This helps play on natural instincts to keep their play and sleep area clean. By 5-8 weeks of age puppies are well trained and rarely have accidents. This helps immensely with the transition to house breaking and crate training. This also helps in the beginning months if you have to leave you puppy alone for extended periods of time. You can set them up in a small area with food, water, and a litter box and they are self sufficient and much cleaner in their habits.